Ill 



result is given in the table below, indicating bow 

 many cc. of the mixture, - - containing per cc. 1 milli- 

 gram of lysin and n parts '/40% antitoxin -- are neces- 

 sary to produce a certain degree of haemolysis (7). It 

 appears from the table that the amount necessary (the 

 'toxic quantity") increases with the time, which elapsed 

 after the mixture of toxin and antitoxin, kept at 20 C. 



It appears from these ciphers, that the toxicity of the 

 toxin-antitoxin mixture continually decreases with the 

 time. In the case of mixtures, containing small amounts 

 of antitoxin (n=0.1) this decrease -- that is the from the 

 table apparent increase of the ''toxic quantity" viz. the dose, 

 necessary to produce the given degree of haemolysis - 

 seems to have finished even before the first time of ob- 

 servation viz. 10 minutes after the mixture. At the time 

 all the experiments ought to give the same value, 

 viz. 0,23. 



In the case of greater additions of antitoxin (n=0,5) 

 the dose necessary increases rapidly with the time within 

 the observed interval of time with about 50 % between 

 the time t 10 and t = = GO. (It probably depends on 



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