VI 



days rapidly, later more gradually and on the 19 / 5 , one 

 month after the injection, the blood possessed no more 

 agglutinating property. 



After the injection of 400 cc. typhoid agglutinin (from 

 goat) on another normal goat results quite analogous 

 were obtained (curve No. 7). 



It appears from curve 8, that a rabbit, A, after an in- 

 travenous injection of 10 cc. typhoid agglutinin (from 

 rabbit) showed a rise in agglutinin from to 62,5. Al- 

 ready on the following day the strenght had fallen down 

 to about the half amount, 36, and the fall was con- 

 tinued during the following days. 



Injection of 100 cc. of the same serum on rabbit B 

 increased the agglutinating power of its blood from 

 to 91. The following fall was still more rapid viz. to 

 37 in the succeeding 24 hours, but got more and more 

 gradual, and one month later, the 8 / 6 , all agglulinin had 

 disappeared. 



It is thus apparent that the general features of the ag- 

 glutinin curve are the same for goats, injected with goat 

 serum, as for rabbits, injected with rabbit serum. Now it 

 was of interest to see, //' the agglntinins, produced in dif- 

 ferent species, were identical or not. To settle this question, 

 the agglutinin curve was examined in animals, on which 

 agglutinin from another species was injected. 



Curve No. 9 represents 2 rabbits and 3 cats, which 

 got an injection of 1012,5 cc. typhoid agglutinin from 

 goat. One rabbit and one cat died the next day under 

 a sudden fall of agglutinin, these animals being not able 

 to stand greater quantities of foreign sera. It appears 

 from the 3 other experiments, that both in the cat and 

 in the rabbit all agglutinin had entirely disappeared 

 within 56 days after the injection. 



20 



