X 



bourhood of the vessels. The greater part of them are 

 found in the fissures of the connective tissue, often 

 several together. Their nuclei resemble those of the 

 fix connective tissue cells between which they lie. Trans- 

 itory forms and figures, which seem to make it likely 

 that they originate through a direct division of the con- 

 nective tissue cells, are found in the preparations. 



Guinea-pig 5 (24 hours}: 



In sections from guinea-pig 5 (twenty-four hours) 

 the angular and the starshaped yeast cells are more 

 numerous and the break down of the yeast altogether 

 more manifest. The number of mononuclear cells 

 among the yeast cells has increased, a few unchanged 

 connective tissue corpuscles still being visible. 



In several places the mononuclear wandering cells 

 gather in little heaps round the yeast, and in several 

 places the border-lines between the individual cells 

 are indistinguishable. Evidently we have before us 

 the beginning of a giant cell formation (s. Fig. 3). 

 Quite exceptional binucleate cells appear; some of these 

 are still fusiform, but they have distinctly increased in 

 size; others show a contraction of the protoplasm be- 

 tween the nuclei. Only very few karyokinetic figures 

 are seen partly as spirems, partly as single stars. 



It was not possible to show any difference between 

 white blood-corpuscles, mononuclear wandering cells and 

 the fixed connective tissue cells with triacid or Ehrlich- 

 Biondi-Heidenhain's mixture. The protoplasm in all of 

 them was stained a faint reddish colour without dis- 

 tinct granular delineation; whereas distinctly reddish 

 granules were seen in the above-mentioned granular 

 cells on using these stains. 



10 



