BOWMAN LECTURE. CXXIJI 



blindness " or " day-blindness." A large unclassed residue 

 remains, but in all probability had attention been paid in 

 these cases to the colour-sense and to the pigmentation 

 of the eye some of them would have been placed in one 

 or other of the two categories just named. 



I have nine or ten pedigrees illustrating nystagmus in 

 families affected by what I look upon as incomplete 

 albinism limited to the eyes, ten of nystagmus with day- 

 blindness or total colour-blindness, and fifteen of unclassed 

 nystagmus. 



(a) ALBINISM. 



(Fig*. 54 and 55 in text ; 53, and 56 to 60 in Appendix VII a.) 



What little I have time to say about albinism must be 

 in connection with the incomplete or partial cases that, as 

 I believe, have often hitherto been entered as hereditary 

 nystagmus. Pedigrees of ordinary conspicuous albinism 

 with and without consanguinity, with continuous or dis- 

 continuous descent, and with, as well as without, other 

 correlated or coincident disease, are seen in Figs. 56, 

 57,58, 59, 60 in Appendix VII.* A typical case of 

 the slight degree of albinism in which the deficiency 

 of pigment falls mainly upon the eye is seen in Fig. 

 53 (Appendix VII) (Mr. Jameson Evans's case). Here 

 a child set. 15 months (Gen. IV, 1), had nystagmus, 

 slight pink reflex from the pupils, grey irides, and 

 nearly white hair; whilst its brother, when seen at 

 six weeks old, had steady eyes, black pupils, grey-blue 

 irides and yellow hair, " not so light as the elder one at 

 fifteen months old." The one marked III, 9, aet. 8 

 years, with slightly pink pupils, grey irides, decided 

 lack of pigment in choroid, nystagmus, from 2 to 3 D. of 

 astigmatism and V., corrected, - 2 ^, had hair of a light 

 shade of dull-brown which had formerly been lighter. 

 The prevalent hair-colour in the others was dull brown 

 and the irides grey. .In this family with nystagmus, had 



* From a forthcoming memoir upon albinism by Professor Karl 

 Peason, Mr. Usher, and the writer. 



