BOWMAN LECTURE. CXXXVIJ 



APPENDICES. 



The following appendices will enable the reader to verify the more 

 important statements made in the Lecture, especially those as to the 

 numbers of diseased to normal, the relative liability of the two sexes to 

 be affected by each of the diseases in question, and the occurrence of 

 anticipation. In some cases the data themselves are given, in others 

 specific references are made to papers I have lately published which 

 contain the necessary information. 



The subject of Leber's disease is so important that I have thought it 

 well to make a short abstract of every case published and unpublished 

 that I could lay hands upon, and to insert figures of the pedigrees of a 

 large number; this collection is based primarily upon Hormuth's Dis- 

 sertation,* published in 1900, towards which the considerable series pub- 

 lished by Habershon in our Transactions (vol. viii, 1888) furnished an 

 important contingent. A number of other cases, piiblished and unpub- 

 lished, have been added to Hormuth's series. 



The illustrative cases and figures are numbered serially from 1 to 188. 

 Of these, 47 are inserted in the text of the Lecture, the remainder appear 

 in the appendices in connection with their respective diseases. Although 

 this plan will cause some inconvenience to the reader, it is preferable to 

 the alternative of having two separate series of numbers, one for the 

 Lecture, the other for the Appendices. 

 The following are the Appendices : 

 I. Illustrating the introductory section of the lecture. 

 Frequency tables for : 



(A) Cataract, post-natal. 



(B) congenital, lamellar and discoid. 

 (c) other forms. 



(D) Retinitis pigmentosa, continuoiis descent. 



(E) discontinuous descent. 



(F) Diseases allied to retinitis pigmentosa. 



(G) Night-blindness, continuous descent. 

 (H) discontinuous descent, 

 (i) Leber's disease. 



(j) Proportion of females carrying disease in certain sex- 

 limited affections. 



II. Relative numbers of males and females affected by lamellar 

 cataract and other forms of congenital cataract. 



III. Glaucoma, Case-figs. 28-34. 



IV. Retinitis pigmentosa, Case-figs. 37, 38, 39. 

 V. Night-blindness without changes. 



(a) References. 



(6) Mr. W. J. Cants' new case of congenital night-blindness, 



Case and Fig. 44; also Case 41a. 



* Hormuth (Philipp), " Beitr. z. Lehre v. d. hereditiiren Sehnerven- 

 leiden," Inaug. Dissert., Heidelberg, 1900; published also in Detitsch- 

 mann's Beitr. z. Augenheillc., 89, Heft 42. 



6 



