CLXVI1I 



BOWMAN LECTURE. 



1909, with good sight), and 5 daughters, all good sight ; III, 4 affected at 

 21, seen at 25, living in 1909 and has 5 normal children ; III, 7, one eye 

 only aft'ected at 6, and still same in 1909 ; III, 10 affected at 6, seen at 

 13, and heard of in 1909 as in same state at 30, unmarried. The 3 

 daughters, III, 5, 6, and 8, aged in 1909 about 40, 39, and 35 years, have 

 19 children, all normal. 



1891.* Case 111. Sym, Edin. Med. Journ., xxxvi, p. 1133. 



I, 2 affected at 51, living at 75 ; her ascendants not known. II, 1 

 affected at 26 ; II, 3 affected soon after severe cupping for yellow fever at 

 20, now 47 (1891) ; II, 4 at 33 ; II, 5 at 25, now 36, has two sons of 8 and 

 6 (1891) (III, 3 and 4). Ill, 1 and 2, set. 18 to 12 years, all normal. 



1892.* Case 112. Despagnet, Soc. Franc. d'Ophtalmol, p. 392. 



I, 1 to 4 all normal. II, 3, first wife of 4, issue normal ; 1, 2, and 4 all 

 normal ; II, 4 died at 62, alcoholic ; II, 5, second wife of 4, died at 58 ; of her 

 siblings, II, 7 failed in sight at 50, cause unknown, died at 52. Ill, 3 

 affected at 26,41 at record; her "eldest son," (IV, 1) affected at 20, 

 papillitis chiefly L. V. in L., normal in R., F. contracted. Ill, 4 at 30 ; 

 III, 5 at 31, married at 27 ; III, 6 at 32, married a.t 28 ; III, 7 doubtful, 

 slight case, at 30. No consanguinity. (Cf. Case 110.) 



1892.* Case 113. Somya, K.M.f.A., xxx, p. 256. 



Vague history of similar blindness in ascendants of I, 1 and 2. II, 2 

 affected at 34, II, 3 at 28, II, 5 at 18, seen by author ; II, 6 and his 

 ascendants normal. Ill, 1 " blind," III, 2 very amblyopic but exact data 

 wanting. Ill, 3 affected at 19, seen by author. 



1892.* Case 114. Thompson (J. Tatham), T.O.8., xii, p. 156. 



A man, set. 37 years, E.. affected about two months before L., typical, 

 except for a small hsemorrhage in L. retina near O.D. in early stage 

 when neuritic appearances were present. A brother of his mother was 

 " blind " from " disease of optic nerves." 



1896. Case 115. Ogilvie (F. Menteith), T.O.S , xvi, p. 3. 



Three brothers in childship of 16 ; II, 4 affected at 24 ; II, 9 at 27 ; II, 



