BOWMAN LECTURE. 



CLXXJX 



II, 1 affected at 20, died of dropsy at 32 (1889), would be 48 in 1905, no 

 recovery ; II, 2 affected at 25, seen at 35 (1905), no recovery, married 



IE i 



at 28, no issue ; II, 4 affected at 21 (1905), seen soon after, skull unsyni- 

 metrical, slight proptosis on both sides from shallowness of orbits. 



1898.* Case 166. Raymond (F.), Lerons sur la Maladies du Systeme 

 Nerveux. Troisieme serie (Annee, 1896-97), Paris, 1898, p. 399. Author's 

 Family 1. 



I, 1 and 2, first cousins, but kind of cousinship not given. II, 1 died 

 of diabetes at 43 ; II, 2 living, 86 at record ; II, 3 became rapidly blind 

 at 30, probably optic atrophy, died at 49. Ill, 1 died at 43, cerebral 

 tumour; III, 3 at 51, cerebral softening ; they had a son, IV, 4 (author's 



F.q.l&G 



rc.S *<S s Alo6 600 



" T ][: T^s-b 789 



Case 2), affected by typical Leber's disease at 26, seen at 38, no recovery ; 

 syphilis two years before failure of V. Ill, 4 affected at 24, seen at 

 53, said to have remained the same for 20 years, and then improved to 

 reading largish letters ; for years could only with difficulty see to go 

 about (author's Case 3). IV, 3 affected at 22, seen at 26, somewhat 

 improved, V. i at record (author's Case 1). (Indicating numerals to IV 

 omitted in error.) 



