CLXXX BOWMAN LECTURE. 



1898.* Case 167. Ibid. Author's Family 2. 



I, 1 gouty. Ill, 3 affected at 24, seen soon after (author's Case 4) ; 

 III, 1' affected at 23, seen at 46, when he was absolutely blind and had 

 paralysis agitans (author's Case 5). II, 1, 2, and 4, all suffered from 

 same disease at almost same age as the other two. II, 3, 5, 6, died 

 young ; II, 7 died at 18. 



1907.* Case 168. Coste, These pour le doctorat en Medicine, Toulouse. 



Four cases with typical symptoms and mode of descent ; consanguinity 

 of paternal ancestors of one case, but no cases of the disease on that side. 

 Narrow base of skull in some of the affected ones, but this still more 

 marked in III, 2 frem unaffected division. No miscarriages, and apparently 

 no early deaths. Ages in I V : 1 was 27 in 1907, 3 was 17, 6 was 16. Ill, 

 6 married at 1 9 ; only two children, IV, 1 born five years, and IV, 2 ten 

 years after marriage ; both labours natural, no forceps. Ill, 4 affected 

 at 23, 58 at record (1907), unmarried (author's Case 2) ; III, 7 affected at 



35, 48 in 1907 (author's Case 3) ; III, 8 affected at 48, 53 in 1907 (author's 

 Case 4). IV, 2 affected at 2, seen six months later. Ill, 9 had gross 

 central choroiditis in both when seen at 42 in 1907, with V. much reduced 

 and My. 2 D. 



1909.* Case 169. Bach, Munchen med. Wochenschr., p. 210. 



I, 1 to 4 normal. II, 2 affected, her sister normal. Ill, 1 normal, her 

 three brothers affected, two with reduction of V. to fingers at 2 m., the 

 other to V. T "g in E., f in L. IV, 1 affected at 15, seen three months 

 after. 



1909.* Case 170. Mr. Eayner D. Batten, T.O.S., February llth, 1909. 



Single case in boy coming on at 8 in September, 1908, with slight 

 neuritic appearances. V. went down to E. % L. T /^, with Fs. much 

 reduced, then, at end of December, began to improve rapidly, and by end 

 of January, 1909, V. was in each, E. betfcer than L. No other cases 

 known, but mother very ignorant of the family history. 



