CXCVI BOWMAN LECTUEE. 



the childship not given. II, 6, set. 84 years at date of first record, and 

 still living (May, 1909) ; eyes affected for more than fifty years ; the 

 cornese are densely opaque and scarred, and it cannot now be proved 

 that she has the family disease ; her only child, Daniel, set. 56 years 

 (III, 14) has normal eyes. II, 5, Karoline Wolf, set. 72 years and 

 still living (May, 1909), has had the family disease all her life. Ill, 

 1, Karl Bienert (the younger), 63, has had the corneal disease thirty 

 years. Ill, 2, Ferdinand Bienert (the elder), died at 36 in 1876; had 

 the family disease and his sight was very bad. Ill, 3, Josef Bienert, 

 53, cornese clear but iris shows remains of foetal pupillary mem- 

 brane. Ill, 4, Edward Bienert, died at 30 in 1879, believed to have 

 had good sight. Ill, 5, Antoine Bartosch, 49, and III, 6, Johann 

 Bienert, 48, both typically affected. Ill, 7, Wenzel Wolf, 50, affected, 

 but sight still relatively good. Ill, 8, Ant. Wolf, 48, affected and sight 

 very bad. Ill, 9, Karoline Beer, died at 43 between 1890 and 1900, was 

 affected by the family disease, but is said to have still seen well. Ill, 

 10, Berta Jung, 45, affected and sight very bad. Ill, 11, Leopold Woll- 

 mann, 41, affected and sight very bad. Ill, 12, Matilda Rosier, 39, 

 affected, but sight stiU good. Ill, 13, Marie Wolf, 17 (? 37), affected, and 

 sight very bad. Ill, 14, see II, 6. IV, 1, Emil Bienert, 39, affected. 

 IV, 2, Frau Engelfeld, about one year younger than IV, 1, reported to be 

 normal, as also her six children, but could not be seen (May, 1909). IV, 

 3, Karl Bienert (the third), examined at 13 (? 1900), high myopia but no 

 corneal disease. IV, 4, Karl Bienert (the fourth), 31, and his sister, IV, 

 5, Auguste, 29, both affected. IV, 6, Ferdinand Bienert (the younger), 

 26, moderately high myopia, no corneal changes. IV, 7 and 8 examined 

 and normal ; IV, 9 died at 24 nearly blind, but believed not to have had 

 the " Bienert disease." IV, 10, Hedwig Bartosch, 23, affected. IV, 11 to 

 18, eight children of III, 6, examined, June 1909 ; IV, 17, Max Bienert, 5, 

 " already shows small, spotted, sub-epithelial opacity of both cornese ; it 

 extends to the periphery of the cornea, and the corneal surface is at 

 present smooth ; it is not altogether identical with the family disease." 

 The other seven, IV, 11, Marie, 20; 12, Hans, 19; 13, Eleonore, 17; 14, 

 Margarete, 11 ; 15, Walter, 9 ; 16, Curt, 8 ; and 18, Gerda, 1 year, are normal. 



IV, 19 to 21, Karoline Jung, 26, Emma. 11, and their siblings, no informa- 

 tion obtainable. V, 1 to 4, examined in 1902 and again in May, 1909 : 



V, 1, Mathilde Bienert, 14, normal, and is still normal in May, 1909, set. 

 21 years ; V, 2, first seen at 10 with normal cornese ; when re-examined 

 at 17 (May 1st, 1909) characteristic changes in the cornese ; the same is 

 true of V, 3, normal when seen at 8, the same corneal changes at 15 ; and 

 of V, 4, normal at 4 and characteristically diseased at 11. In the figure 

 Gen. VI, 1909, should have been V. 



Fig. 68. Doyne and Stephenson, The Ophthalmoscope, in, 213 (1905). 



I, 1, eyes bad from youth, and towards end of life sight so bad that 

 she had to be led about ; died at 65. II, 2 seen at 48, with very 

 advanced opacity of E., and less of L. ; age of onset 39, or perhaps 

 earlier. II, 4, a sister, now dead, said to have had the family disease. 



