THE CLEAVAGE OF PROTEINS WITH ALKALI 115 



nucleic acid and the nucleates are the only nucleo com- 

 pounds in which the ratios are at all comparable with 

 those given in the preceding table. Nuclein contains a 

 little less phosphorus than any of these preparations from 

 the germ, while other nucleo compounds are much richer 

 in nitrogen and poorer in phosphorus. It is perhaps worthy 

 of mention that contact with mineral acid apparently 

 breaks up the nucleic acid, the phosphoric acid going into 

 solution; thus, preparation A gives evidence of phosphorus 

 in inorganic combination, while G does not." 



Substance. 

 Nucleic acid 

 Nucleic acid 

 Nucleic acid 

 Nucleic acid 

 Nucleic acid 

 Nucleic acid 

 Nucleic acid 



Inosinic acid 



Clupein nucleate 



Nucleohiston 



Nucleoprotein 



Nucleoprotein 



Nuclein 



Ba a-nucleate 



Ba /3-nucleate 



Source. 

 Salmon sperm 

 Sea urchin sperm 

 Yeast 

 Pancreas 

 Thymus 

 Thymus 

 Wheat embryo 



Muscle 



Thymus 

 Thymus 

 Pancreas 

 Pancreas 

 Thymus 

 Thymus 



In a later paper, Leach 1 has made a study of the hapto- 

 phor of egg-white. The percentages of ash, nitrogen, phos- 

 phorus, and sulphur in egg-white and its split products 

 are given and compared with the cellular substance of the 

 colon bacillus in the following table: 



Egg-white . 

 Toxophor . 

 Haptophor . 



Cell substance 

 Toxophor . 

 Haptophor . 



s. 



2.66 

 2.19 

 2.79 



Nash 

 free. 

 14.70 

 13.90 

 14.53 



Pash 

 free. 

 0.138 



0.290 



Sash 

 free. 

 2.73 

 2.22 

 3.20 



7.52 3.990 



1 Jour. Biol. Chem., 1908, v, 253. 



