390 PROTEIN POISONS 



The myocardium shows slight increase in hemofuscin, 

 and there seems to be an excessive fragmentation of the 

 muscle bundles (myocardite segmentaire of Renault). 

 However, this may be due to the fixing fluid. The most 

 striking thing is the occurrence of numerous miliary hemor- 

 rhages into the muscle substance, forcing the fibers apart 

 in places. There is a diffuse distribution of blood throughout 

 the heart muscle, blood cells being found here and there 

 outside the capillaries in the muscles, forcing the fibers 

 apart as though there had been a general diapedesis. The 

 ventricular cavity shows a homogeneous red clot. The 

 lungs show marked acute, passive congestion and localized 

 areas of moderate congestion. There are a few small 

 hemorrhages near the veins along the bronchi and also 

 beneath the pleura. The liver shows extreme passive 

 congestion, all the capillaries being gorged with blood. 

 The whole liver substance appears as though soaked in 

 blood, which lies everywhere, between the liver cells and 

 in the bile capillaries. Some of the smaller ducts contain 

 blood. The liver cells have a cloudy appearance and the 

 nuclei are farther apart than normal, due to the engorgement 

 with blood. The kidneys show some cloudy swelling and 

 marked acute passive congestion. A condition similar to 

 that seen in the heart and liver is found throughout the 

 kidney. The renal tissue is full of miliary hemorrhages, 

 and appears to be soaked in blood. Everywhere between 

 the tubules and scattered throughout the parenchyma are 

 red blood cells. Many of the glomeruli have red blood 

 cells lying free within Bowman's capsules, and the capillaries 

 of the tufts are extremely dilated. The epithelium of the 

 proximal convoluted portion of the tubules is markedly 

 desquamated. Many of the collecting tubules contain 

 pale blood cells which have lost their hemoglobin. The 

 pelvic fat is in part displaced by large suggillations of blood, 

 and there are a few areas of coagulated blood around the 

 kidney capsule. The pancreas is passively congested and a 

 portion of this organ has been included in a large clot in the 

 retroperitoneal region and is wholly necrotic. There is also 

 marked fat necrosis and infiltration of the tissue with blood. 



