f ' 



PROTEIN FEVER 391 



In sensitized rabbits killed by injections repeated after 

 six months, Morse has found the microscopic lesions of the 

 same character, but much less marked than those described 

 above as resulting from acute poisoning. In fresh rabbits 

 hemolysis and hemorrhage seem sufficient to account for 

 death, but this does not appear to be the case in sensitized 

 animals dying suddenly from relatively small doses. 



The Effects of Intravenous Injections of Laked Human Red 

 Corpuscles on the Temperature of Rabbits. The blood was 

 drawn into a solution of sodium citrate, and the corpuscles 

 thrown down in a centrifuge. The corpuscles were repeatedly 

 washed with physiological salt solution, and then dissolved in 

 distilled water and diluted to the volume of the original blood. 



One dose of 5 c.c. of this solution was injected into the 

 ear vein of rabbit No. 7. The highest temperature of the 

 fore period was 101.8. The effects of this injection are 

 shown by the following figures: 



Time. Dose in c.c. Temperature. 



8.00 A.M. 101.8 



9.00 5 101.5 



11.00 104.2 



12.00 105.2 



1.00 P.M. 106.0 



2.00 105.6 



3.00 105.6 



4.00 104.7 



5.00 104.2 



6.00 104.0 



8.00 A.M. 101.8 



In No. 10, 2 c.c. of the same solution had the effect 

 shown in the following: 



Time. Dose in c.c. Temperature. 



8.00 A.M. 103.0 



10.00 2 103.1 



11.00 104.4 



12.00 105.6 



1.00 P.M. 107.0 



2.00 106.4 



3.00 106.2 



4.00 105.6 



6.00 104.6 



8.00 A.M. 102.8 



12.00 . 102.6 



