422 



PROTEIN POISONS 



Fig. 25 represents four rabbits which were given 0.5 c.c. 

 each of cancer-cell vaccine by different methods. The first 

 was given a simple subcutaneous injection of rectal adeno- 

 carcinoma. The fourth represents the same amount of 

 the same tumor given intraperitoneally, as does also the 

 third. The second shows the injection of vaccine made 

 from a rapidly growing round-celled sarcoma of the neck. 



B C D 



.11.1.1111.8.1111.3-11 11.2-1111-3-1111-4-11 10-lC-ll 10-17-11 10-18-11 10-lC-ll 10-17-11 10-18-11 



FIG. 25. A, rabbit given subcutaneous injection of 0.5 c.c. rectal 

 adenocarcinoma (Morris) ; B, rabbit injected with 0.5 c.c. small round-celled 

 sarcoma; C, rabbit given intraperitoneally 0.5 c.c. rectal adenocarcinoma 

 (Morris) ; D, rabbit given intraperitoneally 0.5 c.c. rectal adenocarcinoma 

 (Morris). 



From these charts it can be seen that the intraperitoneal 

 method of injection gives a more rapid reaction than the 

 subcutaneous. 



Fig. 26 illustrates the blood changes occurring in a sheep 

 following the injection of 0.5 c.c. of sarcoma residue. 



Figs. 27 and 28 show more frequent differential counts 

 following repeated subcutaneous injections. 



