APPENDIX 



183 



CASE OBBABD, A., aged 21. Patient, who had never been abroad before, left England on 

 June 1, 1915, and went direct to the Peninsula (Cape Hellas and Suvla Bay). While there 

 he had attacks of diarrhoea, was wounded, and finally transferred to Alexandria. On April 2, 

 1916, during the routine examination of cooks in Mustapha Camp, patient was found to be 

 a carrier of E. histolytica. He had also an infection of E. coli. There was no history of 

 dysentery and patient had never had emetin. He was kept under observation till April 11, 

 when a course of emetin injections (one grain a day for 12 days) was commenced. The 

 cysts of E. histolytica disappeared at first hut they recurred before the end of the course 

 and were just as numerous afterwards. Patient was observed till May 3 when a second course 

 of emetin for 12 days was given (one grain injection each morning and \ grain in keratin- 

 coated tabloid by the mouth at night). The day after treatment was commenced no cysts 

 of E. histolytica were found and they did not recur during a control of 48 days after the 

 course was completed. Unfortunately no stool was examined on the day the course was 

 commenced, but the E. histolytica cyst had been passed regularly up to that date. During the 

 first course of emetin patient was not kept in bed and was given chicken diet, while during the 

 second course he was in bed on milk diet. The emetin by the mouth caused vomiting on three 

 occasions. During the first course of emetin there was a slight increase in the patient's pulse- 

 rate, which persisted after the treatment for a few days. During the second course the increase 

 in pulse-rate was still more marked, and it did not subside for at least a fortnight, and patient 

 complained of shortness of breath on exertion. There was no change in the temperature. 



