xiv CONTENTS 



PAGE 



tion Bacillus of plague Microscopical characters Cultiva- 

 tion Anatomical changes produced and distribution of 

 bacilli Experimental inoculation Paths and . mode of in- 

 fection Toxins, immunity, etc. Methods of diagnosis 

 Relapsing fever and African tick fever Characters of the 

 spirillum Relations to the disease Immunity African 

 tick fever Malta fever Micrococcus melitensis Relations to 

 the disease Mode of spread of the disease Methods of 

 diagnosis Yellow fever Etiology of yellow fever . . 420 



CHAPTER XIX. 

 IMMUNITY. 



Introductory Acquired immunity Artificial immunity 

 Varieties Active immunity Methods of production At- 

 tenuation and exaltation of virulence Passive immunity 

 Action of the serum Antitoxic serum Standardising of 

 toxins and of antisera Nature of antitoxic action Ehrlich's 

 theory of the constitution of toxins Antibacterial serum 

 Bactericidal and lysogenic action Haemolytic and other 

 sera Methods of hsemolytic tests Opsonic action Ag- 

 glutination Precipitins Therapeutic effects of anti-sera 

 Theories as to acquired immunity Ehrlich's side-chain theory 



L- Serum anaphylaxis Theory of phagocytosis Natural 

 immunity Natural bactericidal powers Natural suscepti- 

 bility to toxins ....... 456 



APPENDIX A. 

 SMALLPOX AND VACCINATION. 



Jennerian vaccination Relationship of smallpox to cowpox 

 Micro-organisms associated with smallpox The nature of 

 vaccination ....... 503 



APPENDIX B. 

 HYDROPHOBIA. 



Introductory Pathology The virus of hydrophobia Prophylaxis 



Antirabic serum Methods . . 510 



