ANTHEAX IN ANIMALS 307 



mixed with red corpuscles and leucocytes, chiefly lymphocytes 

 and the large mononucleated variety (Fig. 108). Pieces of the 

 organ may be hardened in absolute alcohol, and sections cut in 

 paraffin. These are best stained by Gram's method. Micro- 

 scopic examination of such shows that the structure of the pulp 

 is considerably disintegrated, whilst the bacilli swarm throughout 

 the organ, lying irregularly amongst the cellular elements. The 



FIG. 108. Scraping from spleen of guinea-pig dead of anthrax, showing the 



bacilli mixed with leucocytes, etc. (Same appearance as in the ox.) 



"Corrosive film" stained with carbol-thionin-blue. x 1000. 



liver is enlarged and congested, and may be in a state of acute 

 cloudy swelling. The bacilli are present in the capillaries 

 throughout the organ, but are not so numerous as in the spleen. 

 The kidney is in a similar condition, and here the bacilli are 

 chiefly found in the capillaries of the glomeruli, which often 

 appear as if injected with them. The lungs are congested and 

 may show catarrh, whilst bacilli are present in large numbers 

 throughout the capillaries, and may also be found in the air cells, 

 probably as the result of rupture of the capillaries. The blood 

 throughout the body is usually fluid and of dark colour. 



