ANTHRAX IN MAN 309 



tions. If a small quantity of anthrax bacilli be injected into the 

 subcutaneous tissue of a guinea-pig a fatal result follows, usually 

 within two days. Post mortem around the site of inoculation the 

 tissues, owing to intense inflammatory oedema, are swollen and 

 gelatinous in appearance, small haemorrhages are often present, 

 and on microscopic examination numerous bacilli are seen. 

 The internal organs show congestion and cloudy swelling, with 



FIG. 109. Portion of kidney of a guinea-pig dead of anthrax, showing the 



bacilli in the capillaries, especially of the glomerulus. 

 Paraffin section ; stained by Gram's method and Bismarck-brown. x 300. 



sometimes small haemorrhages, and their capillaries contain 

 enormous numbers of bacilli, as has already been described in 

 the case of the ox (Fig. 109) ; the spleen also shows a corre- 

 sponding condition. Highly susceptible animals may be infected 

 by being made to inhale the bacilli or their spores, and also by 

 being fed with spores, a general infection rapidly occurring by 

 both methods. 



Anthrax in the Human Subject. As we have noted, man 

 occupies a middle position in the scale of susceptibility to 

 anthrax. It is always communicated to him from animals, and 



