520 HYDROPHOBIA 



trephine which is made for the purpose. Symptoms usually 

 occur in from ten to twenty-three days and death in fifteen to 

 twenty-five days. When such inoculation has to be practised it 

 is evident that the diagnosis is delayed. When the material for 

 inoculation has to be sent any distance this is best effected by 

 packing the head of the animal in ice. The virulence of organs 

 is not lost, however, if they are simply placed in sterile water or 

 glycerin in well-stoppered bottles. When the brain of the 

 suspected dog is available either through its death or its being 

 killed, the Negri bodies should be sought for especially in the 

 cornu Ammonis by the methods described above. 



(b) Treatment. Every wound inflicted by a rabid animal 

 ought to be cauterised with the actual cautery as soon as possible. 

 By such treatment the incubation period will at any rate be 

 lengthened, and therefore there will be better opportunity for 

 the Pasteur inoculation method being efficacious. The person 

 ought then to be sent to the nearest Pasteur Institute for treat- 

 ment. It is of great importance that in such a case the nervous 

 system of the animal should also be sent, in order that the 

 diagnosis may be certainly verified. 



