Effects of Extracts of Posterior Lobe of Pituitary 89 



demonstrates that the autacoid affects not only the blood-vessels of the 

 organ, but also its secreting cells, which it renders more active (or more 





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permeable). The secretion must therefore in these circumstances be induced 

 by a direct chemical excitation of the renal cells by the autacoid, which 

 thus bears the same relation to the kidneys as is borne by the secretine of 

 the duodenum to the pancreas. In this respect also the action of the auta- 



