'I i 



Effects of Ovarian Extracts 



145 



of milk (Ott and Scott). This galactagogue action was found by Mackenzie 

 to be absent in extracts of ovary minus corpus luteum. It resembles that 



Fig. 100. — Effect of extract of corpus luteum of cow on isolated cornu uteri of rat. 

 Marked increase of tone is produced. 



Fig. 101. — Effect of extract of corpus luteum of cow on isolated cornu uteri of rabbit. Inhibition, 

 followed by increased rapidity of rhythm, is produced. (I am indebted to Dr M.Itagaki for 

 the tracings shown in figs. 97, 98, 100, and 101.) 



of pituitrine, and seems to be the result of stimulation of plain muscle in 

 the walls of the mammary alveoli (see p. 94). 



Metabolic Effects produced by Corpus Luteum 



Th. Sack found that if corpus luteum be added to the food of white 

 rats it promotes retention of nitrogen, i.e. laying on of flesh, in females ; 



10 



