266 EPIZOOTIC APHTHA. 



little is written on the subject until 1763 and 1764. Aph- 

 thous disorders, and gangrenous anginse, were very rife 

 amongst cattle, and also amongst human beings, at this 

 period. They were widely distributed over the European 

 continent, and Sagar specially mentions a severe outbreak 

 of epizootic aphtha amongst the domestic animals, and com- 

 municated to human beings. 



No special notice of this disease was published until the 

 beginning of the present century. It was very prevalent in 

 the years from 1809 to 1812. Heusinger publishes the 

 details of an outbreak spreading through Europe, from 

 east to west in 1817. It was also severe in 1824, and 

 several Italian authors then wrote on it. In 1827, the 

 malady committed much damage in various parts of Europe, 

 and in Bohemia the 1 disease was noticed amongst the people. 



In 1834, the foot-and-mouth disease rapidly travelled 

 through Podolia from east to west, and Heusinger specially 

 remarks, that England escaped, as it had done in every 

 previous outbreak. At this time, repeated observations 

 were made as to the communication of the disease from ani- 

 mals to man. Hertwig performed experiments at Berlin, 

 and many cases were reported on, having been witnessed in 

 France. 



From 1834 to 1840, and '41, the disease continued to pre- 

 vail on the European continent. It was very rife in Poland, 

 Eastern Prussia, Hungary, Pomerania, and spread up through 

 Hanover, and Saxony, to Belgium, Holland, and Great 

 Britain. Numerous were the observations there of the disease 

 in the human subject. 



In 1839 the malady was very severe, and its attacks 

 amongst human beings were especially observed. 



Heusinger furnishes us with a table indicating the spread 

 of the disease from east to west. 



