THE LOBTJLAR PARENCHYMA CONTINUED. 



man liver, destitute of a wall. As these channels approach the mar- 

 ginal part of the lobule, the hepatic cells surrounding the capillary 

 are seen to change their form. They elongate, getting thinner, grad- 

 ually losing their form as hepatic cells, and assume a columnar type. 

 At the same time, a few fibres of connective tissue are thrown outside 

 the modified hepatic cells, and a bile duct results. The hepatic cells 

 become, insensibly, the columnar cells lining the duct. This is 



FIG. &4. PORTION OP THE PERIPHERY OF AN HEPATIC LOBULE SHOWING THE ORIGIN OF A BILE: 



DUCT. 

 Stained with Heema. and Eosin. x 400. 



A. Bile capillaries in longitudinal section. 



B. Bile duct. The bile capillaries are simply chinks between the hepatic cells. In order to 

 tte formation of a duct, the hepatic cells are altered in shape, elongated, and eventually become 

 the lining cells of the duct. A little connective tissue, thrown around the outside, completes the 

 structure as seen at B. 



C. Bile capillary in transverse section. The larger clear spaces are blood capillaries. 



shown in the illustration rather diagrammatically. Its demonstration 

 requires much patient study and search. The duct is best traced 

 backward, as these are readily found.) 



