SPHYGMOMANOMETER AND ENDOCRINES 143 
If we take up the phase of hypotension in chronic 
diseases of non-infectious origin, there is very little 
that could be said that has not been said already in 
general regarding the similar conditions in acute in- 
fectious diseases. In both circumstances patients are 
suffering more or less from toxemia, caused by the 
bacterial poison, produced in their development. In 
non-infectious chronic conditions, on the other hand, 
the toxemia is caused by the retention of the products 
of metabolism or as the result of malmetabolism. In 
both classes, generally speaking, we have poor elimina- 
tion, caused in part, at least, by the accompanying low 
blood pressure. [Elsewhere the reviewer has shown 
that the opposite is equally true, i. e., that the deficient 
chemistry favors the hypotension.—H. R. H.] Then, 
of course, a part of the treatment in both of these 
classes of diseases becomes the same—efforts to in- 
crease elimination as nearly as possible up to normal, 
and direct support of the played out glands by the use 
of adrenal substance with the other endocrines by 
measures which act on the urinary and alimentary 
tracts. 
ENDOCRINE ASPECTS OF CANCER 
For over a quarter of a century, the two diseases that 
have received my greatest study and attention are tu- 
berculosis and malignant growths. With cancer, I am 
no longer looking for a germ as the causative factor, 
but I consider cancer from the start to the end as a 
condition due to autointoxication. The breaking out of 
the sore at the site of an old bruise or continued irrita- 
tion is not the beginning of cancer. The foundation for 
the new growth was laid months or even years before 
in chronic autointoxication. If this underlying, pre- 
cancerous condition had not existed, the site of the 
bruise or irritation would not have become the site of 
the cancer, for where one cancer sore develops at a 
