144 THE INTERNAL SECRETIONS—1920 
point of irritation, dozens of people have received a 
similar or greater irritation at the same point without 
a cancer resulting. 
Then the correct treatment of cancer resolves itself 
into two parts: destroy the local condition and free 
the patient from the autointoxication. Surgical treat- 
ment unaided is ineffectual, as shown by the large num- 
ber of recurrences. The apparently successful cases 
are those who by good fortune, either by design or acci- 
dent had their waning blood pressure increased and in 
whom elimination was invoked to the limit. Thus 
adrenal substance became an important adjunct in the 
treatment of cancer. But it is not the only endocrine 
we should use. While some use trypsin internally as 
well as locally and recommend it highly, and undoubt- 
edly it is of great value, dessicated spleen has given me 
better results. In fact, we have reason to believe that 
the spleen stimulates the pancreas, thus increasing its 
trypsin output. While trypsin is supposed to have a 
direct antimalignant effect as a digestant of cancerous 
tissue, the spleen substance is more of a reconstructive, 
particularly a hematinic. Other organotherapeutic ma- 
terials will work in well in the treatment of cancer, 
depending on the organ which is affected by the malig- 
nant growth, and the associated general condition in- 
cluding the functional capacity of the ductless glands. 
SOME CONSIDERATION ABOUT HYPERTENSION 
In considering the other phase of blood pressure, 
hypertension, a number of elements must be studied in 
order to reach any definite conclusions. The hyperten- 
sions are easily classified for study into the organic and 
the functional. 
In the first class, the immediate cause lies in a patho- 
logical change in some vital organ, as, for instance, in 
the kidney as an interstitial nephritis; or in hypertro- 
phy of the heart, or in the arteries as in arteriosclerosis. 
