ADRENAL HYPOFUNCTION 159 
given, and in thirty days she was free of asthma. She 
later became pregnant, was delivered under anesthetic 
at term, and her asthma returned. 
The other case was Mrs. J. H. R., age 23, in 1913 had 
tonsilitis and bronchitis, followed in two weeks by 
swelling of the feet and ankles, which progressed until 
the entire body was swollen. Hypothyroidism was diag- 
nosed and one and one half grains of thyroid were 
given daily. In nineteen days all swelling was gone 
and albumin and casts had disappeared from urine. 
Thyroid feeding was stopped. Since that time to date, 
there has been no return, even though in December, 
1918, she had ‘“‘flu,” and also was delivered, under anes- 
thetic, of a normal male child. 
SUBACUTE FORMS OF ADRENAL INSUFFICIENCY 
Among the subacute cases, we find those following 
severe illness associated with fever, such as typhoid, in- 
fluenza, pneumonia, etc., also anesthesia, alcoholism, 
prolonged worry (which, in fact, is really excessive 
mental work), focal infections and intoxications. A 
recent case will serve to illustrate the pronounced adre- 
nal depression which may be caused by worry. Mrs. 
E. J. W. had been feeling very dizzy and weak for ten 
days. She complained of her head feeling queer. Sys- 
tolic blood pressure 100 mm. erect; 128 recumbent. 
Urine and physical examination negative. Adrenalin 
chloride solution, 1:1000, ten drops every two and one 
half hours, was given by month. Next day, July 14th, 
1920, erect systolic pressure 110; recumbent 120; July 
15th, 1920, erect systolic pressure 116, recumbent 116, 
and she said she felt fine. I then found out that she 
thought she had had lues years ago. When the hot 
weather started she always felt badly, but, heretofore, 
only for a few days. This ill feeling lasted so long, in 
spite of catharsis, etc., that she began to worry for 
fear the old disease was attacking her brain. The 
