XVII 
INVESTIGATIONS OF SOME BIOLOGICAL 
EFFECTS OF ADRENALIN 
By Dr. LEON BINET, Paris, France 
The work that we have the honor of addressing to 
“THE HARROWER LABORATORY” is the result not 
of documents sought for in medical literature, but of 
personal investigation, made in various laboratories 
with the assistance or under the direction of our mas- 
ters, Professors Ch. Achard, H. Richet and H. Roger. 
These inquiries are related to: 
1. The action of adrenalin on carbohydrate meta- 
bolism. 
2. The action on the heart. 
3. The action on shiver (tremor). 
4. Its action in anesthesia. 
5. Its action on tetany. 
The bibliography which follows them is a complete 
list of the publications in which some of these inquiries 
have been expounded. 
I 
THE ACTION OF ADRENALIN ON CARBOHYDRATE 
METABOLISM 
It is now known, since the publication of the work 
of Blum, Zuelzer and Metzger, that the injection of 
adrenalin, either under the skin or into the veins brings 
about glycosuria, and it is proved that this glycosuria is 
connected with an increase of sugar in the blood. This 
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