184 THE INTERNAL SECRETIONS—1920 
icine as well as therapeutics at present engaging such 
prominent men as Barker, Sajous, Cannon, Harrower, 
Kinnicut, Pottenger, Borchardt, Sergent, Perrier and 
many others in its work. 
GENERAL CONSIDERATIONS 
The successful organotherapy of the various endo- 
crinopathies which are either fundamental or incidental 
in children’s disorders involves a broad understanding 
and a knowledge of details, greater, perhaps, than in 
any other line of medical work. Not infrequently it is 
the absence of such knowledge on the part of medical 
men which explains a great deal of the therapeutic 
doubt and skepticism which exist at the present time. 
Therapeutic nihilism in ductless gland therapy as far 
as pediatrics is concerned, and also any other branch of 
medicine, invariably means gross ignorance and incom- 
petence. Without a doubt, a great deal of judgment 
must be used in the study of these cases as well as in 
the selection of these remedies. 
I will now consider the most important of the endo- 
crinopathies that exist in the disorders of children, 
such as nutritional disorders; anomalies of growth and 
morphogenesis; anomalies of the sex glands and repro- 
ductive organs; and certain of the nervous and muscu- 
lar disturbances. 
NUTRITIONAL DISTURBANCES 
There exists an intimate relationship between the 
internal secretions and the growing organism. Ob- 
servations upon the growth and development during in- 
fancy and childhood are of utmost importance. Only 
through such meais are many diseases detected in their 
incipiency. I have divided the various nutritional dis- 
orders into definite types, each being characteristic of 
its associated dyscrinism. 
