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SOME NEW WAYS TO USE LIQUOR HYPOPHYSIS 
By H. E. MACDONALD, M.D., Los Angeles, Calif. 
In the course of several years’ experience with var- 
ious perparations of the active principle found in the 
posterior lobe of the pituitary body, I have become 
accustomed to using this remarkable organotherapeutic 
preparation in several conditions for which I have not 
seen any recommendations in the literature. Also I 
have worked out a method of using Liquor Hypophysis 
in labor which differs materially from the procedures 
outlined in the works of reference at my command. 
GALL STONE COLIC 
In biliary adrenal colic I give a hypodermic of mor- 
phine and after the pain stops I inject intramuscularly 
1 mil. of Liq. Hypophysis. Ordinarily this brings the 
pain back, but within a few minutes the stone usually 
passes. In fact, I have never known it to fail in colic 
of either variety. 
ACUTE APPENDICITIS 
A few days ago I was called at noon to see a large 
man suffering extreme pain from an acute attack of 
typical appendicitis—it being the third time he was 
brought down by this disease. He refused to be oper- 
ated. I relieved him of the pain with morphine and 
then injected 2 mils. of Liq. Hypophysis. He almost 
immediately had three “colicy” pains. Called at 10:00 
P. M.; no return of pain. Next morning the patient 
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