250 THE INTERNAL SECRETIONS—1920 
physical findings were negative througnout, except for 
a slight hypertrophy of the prostate. There was a defi- 
nite mental obsession due to anxiety over his condition. 
After receiving ten injections of the serum the patient 
had improved greatly and had resumed business. His 
nights were comfortable, and he felt much improved. 
Three months after beginning treatment he gained 
back the power of erection and ejaculation. Micro- 
scopical examination of the semen, however, revealed 
the fact that the spermatozoa were not motile. The 
psychological stimulus coincident to the return of the 
function was indeed wonderful in that it changed the 
mental aspect entirely, allowing him to dispel the 
pseudo-obsession under which he was laboring. This 
patient is well and working eight hours every day. 
His mental attitude is cheery, and he looks and acts 
twenty years younger. 
CASE V.—Capitalist, aged fifty-four, past history 
negative as to medical and surgical illness. Has always 
indulged in alcohol to excess. History of sexual indis- 
cretion dates back for the past twenty years. Con- 
sulted me June, 1919, because of inability to maintain 
erection, with partial loss of ejaculative powers. This 
condition had been present for a year. Physical find- 
ings negative aside from hypertrophied prostate. Ad- 
ministration of serum commenced June 15, 1919. Re- 
ceived ten injections in all. On discharge function had 
returned. I may state that there was no medication 
aside from the serum used in this case. This patient 
was of the roué type and the condition was the result 
of fatigue of the endocrine secretion which responded 
to specific stimulation in the form of activating sub- 
stances. 
CONCLUSION 
In none of these cases was there any evidence of dis- 
ease of the interstitial cells of Leydig. In each case 
electric stimulation caused a slight erection of the 
penile musculature, with a short contraction of the 
sphincter muscle. The patient in Case II did not react 
in any way to large doses of strychnine, which led me 
to believe that neurological conditions existed. {n 
