256 THE INTERNAL SECRETIONS—1920 
lapses should not occur without a reinfection, and if 
they do, the reason is a matter which only time can 
elucidate. 
CLINICAL REPORTS 
The cases which follow are briefly reported to indi- 
cate the character of the success of this treatment: 
Mrs. M., 34 years old; was a typical case, and had had 
three serious relapses. Several bad teeth and both her 
tonsils were first removed. The active treatment was 
begun by giving one mil. of Mixed Infection Phylaco- 
gen, which dose shortly was increased to 5 mils. daily. 
The injections were continued for two months. To this 
was added a simultaneous course of tonics, and the pa- 
tient was kept thoroughly at rest in bed. The nutrition 
and blood count were remarkably increased, and she 
has remained normal for five years. 
Mrs. J. had suffered from repeated attacks of quinsy. 
The blood picture was typical of pernicious anemia. 
Relapses were severe and frequent. She had been ill 
for two years. Both tonsils were removed. Treatment 
was as outlined above, which resulted in complete and 
full recovery, which has lasted for over five years. 
Mr. D., 34 years old, ill with typical pernicious ane- 
mia for four years, and during that time he was under 
the care of at least six prominent Colorado physicians. 
Hemoglobin was below 30. The only history of infec- 
tion that was discovered was an attack of jaundice ten 
years previously. An anal fistula had been operated on 
and cured two years before (two months before the 
operation a rectal abcess had developed and the fistula 
thus only had lasted two months). When he came un- 
der my care he had been suffering from repeated slight 
attacks of jaundice. The feet and legs were swollen to 
the knees, and there was an extreme weakness. The 
treatment consisted of one mil. Mixed Infection Phyla- 
cogen gradually increasing to five mils. daily, alternat- 
ing with injections of three-grain doses of a solution of 
sodium cacodylate. Heart tonics were necessary for a 
time, and essence of pepsin was also given for the diges- 
tion. Thyroid was given in small doses. The patient 
came to the office with great difficulty and remained at 
rest in the intervals at home. The prognosis of several 
