416 PHYSIOLOGICAL CHEMISTRY- 



Paralactic acid is supposed to pass into the urine when the supply 

 of oxygen in the organism is diminished through any cause, e.g., in 

 eclampsia, acute yellow atrophy of the liver, carbon-monoxide poisoning, 

 acute phosphorus poisoning, or epileptic attacks. This acid has also 

 been found in the urine of healthy persons following the physical exercise 

 incident to prolonged marching. Paralactic acid has been detected in 

 the urine of birds after the removal of the liver. Underbill reports the 

 occurrence of this acid in the urine of a case of pernicious vomiting of 

 pregnancy. 



CH 2 .CO.NH.CH 2 .COOH. 



PHENACETURIC ACID, 



Phenaceturic acid occurs principally in the urine of herbivorous 

 animals. It may be isolated from the urine of the dog after feeding 

 phenylacetic acid. 1 It is produced in the organism through the synthesis 

 of glycocoll and phenylacetic acid. It is doubtful if it occurs in normal 

 human urine even after the ingestion of phenylacetic acid. It may be 

 decomposed into its component parts by boiling with dilute mineral 

 acids. The crystalline form of phenaceturic acid (small rhombic plates 

 with rounded angles) resembles one form of uric acid crystal. 



HC = C - CH = CH- COOH 



I I 

 UROCANIC ACID, HN N 



NX 



CH 



This acid has been found in the urine of dogs, but not in human 

 urine. It is imidazolyl-acrylic acid. Hunter 2 found it among the 

 pancreatic digestion products of casein. It crystallizes as sickle-shaped 

 crystals. 



PHOSPHORIZED COMPOUNDS 



Phosphorus in organic combination has been found in the urine 

 in such bodies as glycerophosphoric acid, which may arise from the 

 decomposition of lecithin, and phosphocarnic acid. It is claimed that 

 on the average about 2.5 per cent of the total phosphorus elimination 

 is in organic combination. 



1 Sherwin: Dissertation, Tubingen, 1015. 



2 Hunter: Jour. Biol. Chem., n, 537, 1913. 



