ELEVENTH ANNUAL REPORT. 141 



pus discharge acquires -an offensive odor, and the fistulous open- 

 ings are surrounded by exuberant granulations, forming a fun- 

 goid mass. The adjacent tissues become hardened, and the jaw 

 becomes greatly deformed. The tooth sockets undergo extensive 

 ulceration, with the result that the molars become loose, and in 

 many cases fall out. For reasons difficult to explain, actinomyco- 

 sis attacks the bones of the lower jaw much more frequently than 

 those of the upper jaw. 



The actinomycotic lesions in the internal organs are generally 

 rounded masses of different sizes, enclosed in a fibrous capsule 

 cf variable thickness, hard and resistant at the surface, and some- 

 what softened toward the center. 



They are generally slightly elevated above the surface of the 

 invaded tissue, grayish white in appearance, and surrounded by 

 an area of redness. 



Direct infection from actinomycotic animals to man has been 

 doubted and even denied, yet in view of the many cases of suc- 

 cessful innoculation it can not be considered as impossible. The 

 general consensus of opinion is, that there is no danger of persons 

 contracting this disease from eating the flesh of affected animals, 

 provided the visibly diseased portions are removed. 



