APPENDIX. 829 



C a8 H 45 3 NS0 2 + H 3 = C 26 H 40 5 + C 2 H 7 NSO a , or ainido-isethionic 

 acid. Taurocholic acid -|- water = cholic acid and tauriii. Glycin occurs 

 also in hippuric acid. It can be prepared from gelatin by the action of 

 acids or alkalies, and can also be obtained from hippuric acid. 

 Sarcosin or Methyl } ~ TT xrr v / ^-u <NHCH \ T , . 



.7 ,. .'/ r C H ]>() I = CH <nr\ mr* 1 It IS a CO11- 



amido-acetic acid, f 3 7 * \ CO OH. / 



stituent of kreatin, and also of caffeine, but has never been found free in 

 the human body. It may be obtained from these bodies by boiling with 

 baryta water. 



Leucin or Amido- ) c H NQ /^CH^CH CH CH .CH(NH )CO OH 



caproic acid, } 6 13 



occurs normally in many of the organs of the body, and is a product of 

 the pancreatic digestion of proteids. It is present in the urine in certain 

 diseases of the liver in which there is loss of substance, especially in 

 acute yellow atrophy. It occurs in circular oily discs or crystallizes in 

 plates, and can be prepared either by boiling horn shavings, or any of 

 the gelatins with sulphuric acid, or out of the products of pancreatic 

 digestion. 



Guanidin, CN 3 H. f = CNH <tijj 2 ) * s a derivative f U1 ^a, the atom 

 of being replaced by NH. 



Kreatin^ or Methyl f r W 1ST O / PXTT ^ NH > \ 



guanidin acetic acid, f U ^ J3I U ^ = < NCH 3 , CH f , COOH/ 



is one of the primary products of muscular disintegration . It is always 

 found in the juice of muscle. It is formed by the action of guanidin on 

 methyl amido-acetic acid. It is generally decomposed in the .blood into 

 urea and sarcosin, and only appears in the urine as kreatinin. Treated 

 with either sulphuric or hydrochloric acid, it is converted into kreatinin; 



thus 



C 4 H. N, 3 = C, H, X 3 O + H a O. 



It has been made synthetically by bringing togetlier cyanimide and 

 sarcosine. 



Kreatinin, C 4 H 7 N 3 ( CNH< | ) is present in human 



V N(CH 3 )CH 2 / 



urine, derived from dehydration of kreatin. It does not appear to be 

 present in muscle. It is basic, having lost the COOH group, and reacts 

 as an alkaline body, combining with salts to form double salts, etc. On 

 decomposition it yields urea, sarcosin, and methyl guanidin. 



Taurin or Amido- i / c H SO H\ ^ ft coustituent 



\ iNH., / 



isetkionic acid, y .* 

 of the bile acid, taurocholic acid, and is found also in traces in the 

 muscles and lungs. It has been prepared synthetically from isethionic 

 acid. It is a crystalline substance, very stable. 



