AM(EBJE OF THE INTESTINAL TRACT. 157 



the rapidly growing connective tissue. In the large 

 abscesses, which have a rather thick wall, sections show 

 at the inner border of the abscesses more or less 

 necrotic material, while externally the fibrous tissue 

 is very marked, the appearance being that of granu- 

 lation tissue, the cells of which are mostly uninuclear. 

 More externally is a layer of less dense connective 

 tissue infiltrated with spindle cells and small round 

 connective-tissue cells. This infiltration varies with 

 the age of the abscess. When the fibrous wall is 

 very thick the cellular infiltration is not as great as 

 where the fibrous tissue is of more recent formation. 



The amoebae are found in the abscess wall in the 

 zone of necrosis, generally near the border of the 

 connective-tissue portion of the wall, which is infil- 

 trated by small round cells. From this it will be 

 seen that amoebae will but seldom be found in the 

 very old abscesses showing little necrosis and a very 

 thick and dense fibrous wall. They are found most 

 commonly in the medium-sized abscesses presenting 

 evidences of marked necrosis of the liver tissue. 



In the contents of liver abscesses, which are due 

 wholly to the amoebae, are found shreds of necrotic 

 tissue, degenerative liver cells, red blood corpuscles, 

 granular material, and amoebae. It is remarkable 

 how rare are the pus corpuscles which are found in 

 ordinary pus, sometimes the entire field of the micro- 



