170 PARASITIC AMOEBAE OF MAN. 



could be easily demonstrated in smears made from 

 the intestine, being most numerous where the lesions 

 were most severe, although every part of the large 

 intestine showed infection with this parasite. Smears 

 from the small intestine were negative for amoebae. 



The clinical symptoms in this case were similar 

 to those occurring in all the kittens developing amoebic 

 dysentery and to those occurring in man. The first 

 symptom observed was diarrhoea, the stools being 

 frequent and free from blood at first, but soon be- 

 coming mucoid and bloody and containing numerous 

 amoebae. Fever was generally present and emaciation 

 was rapid. In this kitten the diarrhoea, after per- 

 sisting for several days, ceased, and a period of con- 

 stipation intervened, covering two or three days, after 

 which the dysenteric symptoms returned and from 

 that time until the animal was killed the bowel move- 

 ments varied in number from 6 to 10 a day and 

 emaciation became extreme. Amoeba? could always 

 be demonstrated in the feces after the initial diarrhoea. 



The lesions produced in kittens by the rectal in- 

 jection of material containing Entamceba histolytica 

 are perfectly typical of the lesions of amoebic dysen- 

 tery in man, making allowance, of course, for the 

 lesser extent of the surface involved. 



Feeding Experiments. The most successful 

 results in producing dysentery in kittens with this 



