AMCEBJE OF THE INTESTINAL TRACT. 175 



material, mixed with blood, mucus, and pus. Com- 

 mencing at the rectum and extending for about half 

 the length of the large intestine, the mucous mem- 

 brane was greatly swollen, bright red in color, and 

 contained numerous ulcers. The majority of the 

 ulcers were spherical in shape, the edges were under- 

 mined and greatly thickened, and many were covered 

 in with necrotic tissue. Upon removing this necrotic 

 material the base of the ulcer is found to be formed 

 by the muscular coat of the intestine. The ulcers 

 present were typical of the amoebic ulcerations seen 

 in the intestine of man in every respect. The re- 

 mainder of the large intestine was black in color and 

 gangrenous, the mucous membrane having been 

 almost entirely destroyed, exposing the muscular coat 

 throughout this portion of the intestine. About 4 cm. 

 below the ileocsecal valve there was a small perfora- 

 tion measuring about one-sixth cm. in diameter. 



I believe that it must be evident to anyone from 

 the autopsy records given that the lesions produced 

 in kittens by feeding them with material containing 

 Entamceba histolytica are typical of the lesions of 

 amoebic dysentery in man. The examination of sec- 

 tions of the diseased intestines showed the same micro- 

 scopic pathology observed in sections from the 

 dysenteric intestine of man, and the amoebae were 

 demonstrated in the same situations within the in- 



