AMCEB.E OF THE INTESTINAL TRACT. 185 



in nodular masses and distributed throughout the 

 nuclear substance in the form of a network of minute 

 oval or irregular granules ; the karyosome is large and 

 has a centriola or centrosome, surrounded by a clear 

 area, and in some instances two or three con- 

 centric clear areas surround the centriola; the 

 latter is spherical in shape and varies in size from 

 a minute dot to a comparatively large spherical mass. 



During the reproductive cycle certain changes 

 occur in the karyosome by reason of the rearrange- 

 ment of the chromatin which lead to marked differ- 

 ences in the appearance of the nucleus at different 

 stages of development. 



Vacuoles and Contained Bodies. Vacuoles are 

 not as constantly present in this species as in Enta- 

 mceba histolytica. Very frequently well-grown 

 organisms are observed in which a vacuole is absent, 

 while they are never as numerous as they may be in 

 the latter species. 



This organism is phagocytic for red blood cor- 

 puscles and in feces containing blood the amoebae 

 are usually observed to have engulfed the red cells. 

 So far as I have been able to observe they are as 

 actively phagocytic as Entamceba histolytica. 



The cytoplasm of this species does not contain 

 the small oval bodies which are so frequently found 

 in histolytica, although during certain stages of re- 



