AMQEBJE OF THE INTESTINAL TRACT. 



deeply. The nucleus consists at first of a single 

 mass of chromatin, but later a nuclear membrane is 

 developed. The chromatin assumes a crescentic .shape 

 and separates into two portions which eventually 

 break up into several small masses situated upon the 

 inner side of the nuclear membrane. While these 

 changes are occurring in the nucleus the cytoplasm 

 becomes differentiated into an ecto- and endoplasm, 

 vacuoles appear, and the organism gradually assumes 

 the appearance typical of the fully developed vege- 

 tative stage. 



Encystment is first indicated by a reduction in 

 the size of the parasite, although the oval shape is 

 retained. A delicate cyst wall is gradually developed 

 having a single outline. Some of the chromatin 

 masses of the nucleus become spherical in shape and 

 pass through the nuclear membrane into the cyto- 

 plasm, where they remain unchanged, so far as he 

 was able to observe. The chromatin remaining in 

 the nucleus divides into minute granules which be- 

 come evenly distributed over the inner surface of the 

 nuclear membrane. Koidzumi was unable to follow 

 the further development, so that we are in ignorance 

 of the further changes occurring in the nucleus and 

 of the number of daughter amoeba? which are 

 produced within the cyst. 



RELATION TO DISEASE. The author gives no data 



