244 SPECIFIC MICRO-ORGANISMS 



readily found in the pus by microscopic examination and seem 

 to exist there only as conidia. In cultures a branching mycelium 

 with clusters of conidia is produced. Dogs are susceptible to 

 inoculation. 



Sporotrichium Beurmanii. De Beurmann and Ramond at 

 Paris in 1903 found this parasite in a case of lymphangitis. It 

 seems to be different from the organism described by Schenck 

 but may ultimately prove to be the same species. 



Saccharomyces Cerevisiae. This organism is ,the type of 

 the true yeasts. The cell is spherical or ovoid, and multiplies 

 by budding. Endospores are produced, usually four to eight 

 in a single cell, indicating a rather close relationship to the molds. 

 The organism is found widely distributed, especially on fruits 

 and sugar-containing substances. It has been used for centuries in 

 the leavening of bread and in the alcoholic fermentations. Varie- 

 ties of the species are distinguished by differences in physiological 

 characters, and especially in respect to the amounts of alcohol 

 which they produce. 



Material for study may be obtained from commercial com- 

 pressed yeast, which contains vegetating cells of saccharomyces 

 along with other organisms, or from commercial dried yeast in 

 which the spores are present. Pure cultures may be obtained by 

 plating on gelatin. True yeasts also occur in the gastric juice at 

 times and seem to be able to multiply in the stomach when the 

 acidity of the gastric juice is diminished. 



Blastomyces Dermatidis. Doubly contoured yeast-like cells 

 in human tissues were first discovered by Busse and Buschke 1 in 

 1 894, in a case presenting abscesses in the bones and internal organs 

 together with lesions of the skin. They obtained cultures of the 

 organism and classed it as a yeast. About the same time Gil- 

 christ 2 independently observed similar organisms in cases of 

 dermatitis at Baltimore. The organisms have been most thor- 

 oughly studied by Ricketts. 3 Most of the cases have been ob- 



1 Deutsch. med. Wochenschr., 1895, Nr. 3. 



2 Gilchrist: Johns Hopkins Hosp. Kept., Vol. I, p. 209, 1896. 

 3 Journ. Med. Research, Vol. VI, No. 3. 



