MOLDS AND YEASTS AND DISEASES CAUSED BY THEM 



245 



served in the United States, at Baltimore, at Chicago and in Cali- 

 fornia. One type of the parasite appears to multiply in the tissues 

 by a process of budding (Blastomycetic dermatitis, Blastomycosis) 

 while in other cases, particularly those from California, the 

 spherical bodies found in the tissue seem to multiply by endog- 

 enous spore formation, an appearance which at first suggested 

 the protozoal nature of the parasite and lead to the use of the 



FIG. 101. Doubly contoured organisms found in oidiomycosis (blasto mycosis). 

 (From Buschke after Hyde and Montgomery.) 



unfortunate term, Coccidioidal granuloma. On glucose agar, the 

 parasites usually grow without difficulty and the growth resem- 

 bles that of an oidium, often with abundant aerial hyphae. Inoc- 

 ulation of guinea-pigs with pus or with cultures is usually fol- 

 lowed by formation of abscesses in which the typical spherical or 

 ovdid parasites may be found. The tissue changes have been 

 mistaken for tuberculosis. Further investigations are required 

 to determine the specific relationships of the parasites found in 

 different cases. 



