390 SPECIFIC MICRO-ORGANISMS 



associated with a general enlargement of the lymph nodes. The 

 trypanosomes are numerous in the blood during the febrile period 

 and become very scarce during the intermissions. The fever 

 leads to emaciation and death, sometimes without inducing the 

 terminal coma and sometimes with the production of typical 

 sleeping sickness. The sleeping sickness is characterized by 

 prolonged coma and progressive emaciation. At intervals the 

 patient may be aroused and given nourishment, but eventually 

 this is no longer possible. At this stage the trypanosomes are 

 present in the cerebrospinal fluid. Bacterial infection of the 

 meninges often takes place as a terminal event. It is conserva- 



FIG. 158. Trypanosoma amum in the blood of common wild birds. X 1500. 

 (After Novy and MacNeal.) 



tively estimated that 100,000 natives have died of trypanosomiasis 

 in Africa from 1900 to 1910. There have been several cases in 

 Europeans. Recovery seems to be rather uncommon but does 

 occur. 



Trypanosoma Rhodesiense. Stephens and Fantham 1 have 

 studied a case of human trypanosomiasis contracted in north- 

 eastern Rhodesia, where Glossina palpalis does not occur. The 

 parasite differs somewhat from Tr. gambiense and is regarded by 



1 Proc.lRoyal Soc., 1910, Ser. B, Vol. LXXXIII, pp. 28-33. 



