396 



SPECIFIC MICRO-ORGANISMS 



Sergents. 1 The latter investigators were able to effect experi- 

 mental transmission by means of the dog flea, Ctenocephalus canis. 



Kala-Azar is 'endemic in tropical Asia 

 and northeast Africa, where it occurs among 

 the poorer class of people, living in squalor. 

 It is characterized by irregular fever, weak- 

 ness and cachexia and especially by enormous 

 enlargement of the spleen, often of the liver 

 also. It is frequently fatal. Dogs and mon- 

 keys are susceptible to inoculation. 



LeishmaniaTropica. This organism was 

 first accurately described by J. H. Wright, 2 

 who found it in great abundance in the 

 lesion known as Aleppo boil, Delhi boil or tropical ulcer. 

 The parasites occur within the endothelial cells within the lesion 



FIG. 164. Leishmania 

 donovani, various forms 

 observed in artificial cul- 

 ture. (From Doflein after 

 Chatter jee.) 



IM 



FIG. 165. Leishmania tropica. Smear from a Delhi boil. Xisoo. (From Doflein 



after J. H. Wright.} 



and are very numerous. Leishmania tropica resembles L. donovani 



1 Sergent (Edm. & Et.), L'Heritier and Lemaire, Bull. Soc. Path. Exot., 1912, 

 Vol. V, pp. 595-597- 



2 Journ. Med. Rsch., 1903, Vol. X, pp. 472-482. 





