10 



case of a young woman who wounded her finger with tlie broken edge 

 of a vessel containing sputa (the substance raised from the lungs in 

 coughing) rich in bacilli from a consumptive patient. In a short time 

 there was a swelling as large as a pea beneath the skin. Several months 

 later the trouble had increased to such an extent that the finger was 

 useless, and at the same time the lymphatic glands were more or less 

 swollen. The finger was amputated, and in various places within the 

 tissues were found numerous miliary tubercles which contained the 

 characteristic Bacillus tuberculosis. 



Demet, Paraskev,a and Zallonis, in Syra, Greece, had succeeded to 

 their satisfacti©n in producing tuberculosis iu rabbits by inoculating 

 them with sputa and blood from a man sick with consumption, but 

 they felt that the demonstration would be more complete and convinc- 

 ing, if they could operate on man himself. They therefore selected 

 a patient who was suffering from gangrene in a toe, and whose death 

 was inevitable because of his persistent refusal to allow the diseased 

 member to be amputated. An examination showed that the lungs of 

 the man were perfectly sound and healthy, and that he had not the 

 least tendency to tuberculosis. A quantity of sputa from a consump- 

 tive patient was injected into the upper part of the left thigh. In 

 three weeks an examination of his lungs gave evidence that they 

 were becoming diseased, and at the death of the man, in thirty-eight 

 days, seventeen tubercles were found iu the upper lobe of the right 

 lung, and two in the left lung. 



Dr. E. J. Kempf gives an account, in the London Medical Record, 

 July 15, 1884, of an outbreak of consumption in a Convent in the 

 village of Ferdinand. The inmates had been entirely free from con- 

 sumption up to 1880, but lived a very secluded life, taking very little 

 exercise. The Convent was situated on high, dry ground and was 

 well drained and ventilated, In fact, the hygienic conditions were all 

 that could be desired. In the autumn of 1880, Dr. Kempf was called 

 to attend one of the inmates, a girl eighteen years of age on ac- 

 count of a cough, pain in the chest, and a feeling of general indispo- 

 sition. The girl came from a family which could not be called 

 healthy, and from which a brother of the patient had previously died 

 with consumption. An examination of the girl showed difficult breath- 

 ing, hacking cough, loss of appetite, sleepless nights, weary limbs, a 

 daily fever and difficulty in the apices of both lungs as if from tuber- 

 cular deposits. The patient was not isolated, but slept in the general 

 dormitory with the other inmates. In a short time one after another 



