50 



PHYSICOCHEMTCAL BASIS OP PHYSIOLOGICAL PROCESSES 



Addition or accumula- 

 tion of acid 



Decrease of base 



Addition or accumula- 

 tion of base 



Removal of acids 



Increase of C H . 



Accumulation of CO o (asphyxial conditions). 



Incomplete oxidation of carbohydrate (lactic and in mus- 

 cular exercise). 



Defective oxidation of fat (ketosis). 



Eenal insufficiency (nephritis). 



Decomposition of protein (as in acidosis of fever). 



Intestinal fermentation. 



Administration of acid (experimental). 



Diarrhea and hemorrhage, respectively (may explain acido- 

 sis in cholera and in certain forms of shock). 



Decrease in . 



xi 



Ammonia (faulty metabolism of urea). 



Intestinal putrefaction (infantile conditions). 



Administration of alkalies (experimental). 



Excretion of CO (excessive pulmonary ventilation, as in 



faulty ether administration). 

 Excretion of acid urine. ' 



