466 APPENDIX. 



Beale gives the results of his analyses of one kidney in a state 

 of fatty degeneration, of four diabetic kidneys, and of two diabetic 

 livers. 



Taking the amount of fat in 100 parts of the solid mattery it 

 was found that one diabetic kidney contained five times the normal 

 quantity of fat ; another four times as much ; a third nearly 

 the same proportion; and the fourth contained three times as 

 much as was found in the healthy kidney. The fatty kidney con- 

 tained rather more than six times the quantity of fat (26*97$) 

 obtained in the healthy specimen. 



Of the two diabetic livers, one contained only 4*64, and the 

 other 7'85-- of fat; while in the two healthy livers the corre- 

 sponding numbers were 12'15 and 15'81-g-. 



It woulcl thus appear that in diabetes the kidney, in its chemical 

 composition, approaches to that of fatty degeneration, while the 

 liver appears starved, and its secreting cells seem to manifest 

 a tendency opposite to that of fatty degeneration. G. E. D.] 



(22) Addition to p. 27l 5 H lines from the bottom. These ex- 

 periments of Bidder have, however, most distinctly proved, by the 

 most careful determinations of the excreta in fasting animals, that 

 the elements excreted by the lungs and kidneys cannot solely 

 originate from nitrogenous tissues, but that the excess of carbon and 

 hydrogen excreted by the lungs is entirely to be referred to the de- 

 compositipn of the fat of the starving animal, especially since these 

 determinations of the excreta exactly coincide with the loss of fat 

 directly observed in the dead body of the animal. The daily 

 diminution of the biliary secretion in fasting animals occurs in 

 almost the same ratio as the loss of fat in the body (Schmidt). f 



(23) Addition to p. 280, line 17. Buschjhas applied the term 

 Inosterin to a non-saponifiable fatty matter, which crystallises in 

 needles, fuses at a little above 100, is soluble in cold and hot 

 ether as well as in boiling alcohol, from which it evaporates in an 

 amorphous shape. He discovered it in a uterine tumour ; it 

 probably also occurs in the adventitious products known as 

 collonema and colloid. 



(24) Addition to p. 286, last line. The test proposed by 

 Maumene not only gives precisely the same reaction with 



* Ber. d. kon. sachs. Ges. d. Wiss zu Leipz. 1851. S 162 

 f Verdauungsafte u. Stoffwechsel. Mitau, 1852, S. 386-398. 

 + Mullens Arch. 1851, S. 358. 

 Compt. rend. T. 30, pp. 314 et 447. 



