512 APPENDIX. 



accurate experiments of Wistingshausen * (conducted under 

 Schmidt's superintendence), on the relations of the fats when 

 mixed with the acids of the bile to endosmosis and capillary 

 attraction. 



(13) Addition top. 81, line 20. Moleschott has recently insti- 

 tuted a series of carefully conducted experiments on frogs in relation 

 to this point. Like Kunde, he extirpated the liver ; but succeeded 

 in keeping the animals alive for a longer period. He could not 

 succeed in detecting a trace of the resinous acids or of the pigment 

 of the bile either in the blood or in the lymph, or in the flesh, or in 

 the urine of the frogs on which he operated. It may, therefore, be 

 regarded as an established fact, that the essential constituents of 

 the bile are primarily formed within the liver. 



(14) Addition to p. 112, line 16. The specific gravity of the 

 pancreatic fluid is liable to considerable variations (Ludwig and 

 Weinmannf), since the amount of its solid constituents varies 

 inversely with the time during which the secretion has been going 

 on; Frerichs, who examined a very dilute pancreatic juice, deter- 

 mined its specific gravity at 1*008 or 1*009, while Bidder and 

 Schmidt found the specific gravity of a thick viscid specimen which 

 they were investigating to be 1*0306. 



In correspondence with this density of the pancreatic juice, 

 Schmidt found that on one occasion it contained 9*9 2, and on 

 another 11'56-jf- of solid constituents; in the former case there was 

 9*04 of organic matters, and 0*854 of ash which contained 0*736 of 

 chloride of sodium, the remainder being chiefly bibasic phosphate 

 of soda. 



(15) Addition to p. 114, line 20. The quantity of the pancreatic 

 fluid varies very much in different animals ; according to Colin J 

 it does not stand in a direct ratio to the volume of the gland. 

 While the pancreas of the ox and of the horse yields 260 or 270 

 grammes in an hour, that of the swine, which is about half the size, 

 yields only 12 or 15 grammes in an hour. 



The recent observations of Bidder and Schmidt on the pan- 

 creatic juice of the dog differ considerably from those of Bernard 

 [quoted in the text]. They found that a strong dog (weighing 20 



* Dissert, inaug. Dorp. Livon. 1851. 

 j- Dissert, inaug. Zurich 1852. 

 J Compt. rend. T. 34, p. 85. 



