166 BASIC BODIES. 



they are convinced, contained none of the mother's urine. Mack* 

 and Schererf however, failed in detecting any urea in this 

 fluid. 



[ReesJ has frequently met with small quantities of urea in milk. 



G. E. D.] 



Millon found urea in the vitreous and aqueous humours of the 

 eye, and W6hler|| confirms the fact. 



Urea has very often been found in dropsical exudations. 



I have never been able to discover urea in serous exudations, 

 unless at the same time there was disease of the kidneys ; previous 

 statements may possibly only have reference to dropsical fluids 

 depending on Bright's disease, and not to those accumulations of 

 fluid which arise from enlargement of the liver. 



In Bright's disease, urea is found in all the serous fluids ; thus 

 Schlossberger^j" once found it in an aqueous effusion in the cerebral 

 ventricles. 



The matters vomited in ureemia not unfrequently contain urea. 

 (Nysten** and others). 



Wrightft has found urea in the saliva of a patient with Bright's 

 disease, and also in that of a dog poisoned with corrosive 

 sublimate. 



Urea has been found by O. B. Ktihn in a biliary concretion; 

 and Strahl and Lieberkiihn have recently detected it in the bile 

 after the extirpation of the kidneys. 



Origin. Physiologists were long undecided regarding the seat 

 of the actual formation of urea. Since urea had not been dis- 

 covered in normal blood, many believed that they must adhere to 

 the old view, that the excreta are formed in the excreting organs 

 from the constituents of the blood, and that urea is thus first 

 produced in the kidneys. They accounted for the circumstance 

 that urea is, in certain morbid conditions, sometimes found in the 

 blood and other fluids, by assuming that it was then resorbed from 

 the kidneys or the urinary bladder. To overthrow this opinion, 

 Prevost and Dumas, JJ and subsequently Gmelin, Tiedemann, 



* Arch. f. phys. u. pathol. Ch. u. Mikr. Bd. 2, S. 218-224. 

 t Zeitschr. f. wissenschaftl. Zoologie. Bd. 1, S. 88-92. 



I Guy's Hospital Reports. New series. Vol. 1, p. 328. 

 Compt.rend. T. 26, p. 121. 



II Ann. d. Ch. u. Phann. Bd. 66, S. 128. 

 IF Arch. f. phys. Heilk. Bd. 1, S. 43. 

 ** Joum. de Chim. med. 1837. p. 257. 

 tt Lancet, 1844. Vol. 1, p. 150. 



W Ann. de Chim. et de Phys. T. 23, p. 90. 



