URIC ACID AND THE PURINE BODIES 651 



URIC ACID, UREA N AND CREATININE OF BLOOD IN GOUT AND EARLY AND LATE NEPHRITIS 



(Myers and Fine: Arch. Int. Med., 1916.) 



Lastly, regarding the influence of drugs on the blood uric acid in dis- 

 ease, it has been found by Fine that both atophan and salicylates cause 

 a pronounced decrease in the amount, but that it gradually rises to the 

 old level even while administration of the drugs is being continued. 



Important contributions to the. behavior of uric acid in blood are 

 constantly appearing at present, mainly from the laboratories of Folin 

 in Boston, of S. R. Benedict, and of Myers and Fine in New York. 



