DUCTLESS GLANDS. 355 



reports of these cases attracted a great deal of attention 

 among physiologists as well as pathologists. A year later, 

 Prof. I. E. Taylor, of Bellevue Hospital, reported seven 

 cases of bronzed skin, in two of which the diagnosis of 

 disease of the suprarenal capsules was verified by post- 

 mortem examination. 1 Attention now being directed to this 

 peculiar condition of the system, accompanied with discol- 

 oration of the skin, numerous cases were reported, from time 

 to time, but some of them did not fully carry out the views 

 of Dr. Addison. In 1858, Dr. Harley, in connection with 

 his elaborate researches into the anatomy and physiology of 

 the suprarenal capsules, cited several cases of the so-called 

 Addison's disease, unaccompanied with any disorganization 

 of the capsules, and also several instances in which the cap- 

 sules were seriously invaded by disease, without any bronzing 

 of the skin. 2 Perhaps the most extensive collection of cases, 

 however, taken from a great number of authorities, is given 

 by Dr. Greenhow, in a recent work on Addison's disease. 

 Dr. Greenhow is apparently convinced that the connection 

 between the constitutional symptoms and discoloration of 

 the skin, described by Addison, and disorganization of the 

 suprarenal capsules is well established. He reports one 

 hundred and ninety-six cases ; and, out of these, he selects 

 one hundred and twenty-eight, as fair representatives of Ad- 

 dison's disease. 3 There are several cases (ten) in which there 

 was bronzing of the skin, the suprarenal capsules being per- 

 fectly healthy ; but in only one of these were there any of the 



1 TAYLOR, The Sunburnt Appearance of the Skin as an early Diagnostic Symp- 

 tom of Supra-Renal Capsule Disease. Reprinted from the New York Journal of 

 Medicine, 1856. 



2 HARLEY, An Experimental Inquiry into tftd Functions of the Supra-Renal 

 Capsules, and their Supposed Connexion with Bronzed Skin. British and Foreign 

 Medico- Chirurgical Review, London, 1858, vol. xxi., pp. 204, 498. Shortly after 

 these papers appeared, we made an editorial analysis of them, in connection 

 with the recent observations of MM. Brown-Sequard, Martin-Magron, Gratiolet, 

 and Philipeaux, in the Buffalo Medical Journal (see vol. xiii., 1858, p. 575, and 

 vol. xiv., p. 175). 



3 GREENHOW, On Addison's Disease, London, 1866, p. 47, et seq. 



