86 VACCINE AND SERUM THERAPY. 



of bacterial vaccines. It seems that the injections of killed cul- 

 tures have been both of prophylactic and curative value. The 

 curative value is probably limited to the treatment of chronic 

 diseases, because time is required to actively immunize. More- 

 over this method may be of especial value in the treatment of 

 infections due to species that have many varieties, for here the 

 individual may be immunized to the special organisms causing 

 the disease. Injections of killed cultures will not cure all infec- 

 tions and bacterial diseases and in some cases many injections 

 may be required to obtain the desired result. 



Attention is again called to the fact there is no vaccine for 

 boils, acne or any other condition, but there are vaccines for im- 

 munization against infections by the Mic. pyogenes aureus, albus 

 or citreus, streptococci, typhoid bacilli, pneumococci, gonococci, 

 etc. Vaccine therapy, to give good results, requires that in all 

 infections treated the causal microorganisms or virus must be 

 determined, before vaccines are resorted to. 



Credit is to be given to Wright, not for the discovery of the 

 method of immunization by injections of killed cultures, but for 

 its revival. The employment of this method of inducing immunity 

 and treating bacterial infections and diseases need not necessarily 

 be associated with opsonins and opsonic immunity. 



